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VITAMIN B1 (THIAMIN) AND ITS CHARACTERISTICS
Maqola haqida umumiy ma'lumotlar
Vitamins are chemical compounds that play essential roles in crucial metabolic pathways in all living organisms. Thiamine, also known as vitamin B, was the first B vitamin to be discovered. It acts as a cofactor for numerous enzymes involved in energy metabolism. These thiamine-dependent enzymes are vital for the synthesis of neurotransmitters, the production of substances that protect against oxidative stress, and the creation of pentoses, which are essential precursors for nucleic acids. Thiamine holds a significant position in cerebral metabolism. Insufficient levels of thiamine result in dry and wet beriberi, which manifest as peripheral neuropathy and cardiomyopathy accompanied by edema and lactic acidosis. Additionally, it can lead to Wernicke Korsakoff syndrome
1. Owen R. Fennema (1996). Food Chemistry University of Wisconsin Madison Madison, Wisconsin pp 275 PRINTED IN THE UNITED STATES OF AMERICA
2. Egi, Y., Koyama, S., Shikata, H., Yamada, K. & Kawasaki, T. (1986) Content of thiamin phosphate esters in mammalian tissues – an extremely high concentration of thiamin triphosphate in pig skeletal muscle. Biochemistry International, 12, 385–90.
3. Miyoshi, K., Egi, Y., Shioda, T. & Kawasaki, T. (1990) Evidence for in vivo synthesis of thiamin triphosphate by cytosolic adenylate kinase in chicken skeletal muscle. Journal of Biochemistry, 108, 267–70.
4. Patrini, C., Cusaro, G., Ferrari, G. & Rindi, G. (1981) Thiamine transport by rat small intestine „in vitro‟: influence of endogenous thiamine content of jejunal tissue. Acta Vitaminologicaet Enzymologica, 3n.s, 17–26.
5. Sorrell, M. F., Frank, O., Thomson, A. D., Aquino, H. & Baker, H. (1971) Absorption of vitamins from the large intestine in vivo .Nutrition Reports International, 3, 143–8.
6. Kasper, H. (1970) Vitamin absorption in the colon. American Jour-nal of Proctology, 21, 341–5.
7. Davis, R. E., Icke, G. C., Thom, J. & Riley, W. J. (1984) Intestinal ab-sorption of thiamin in man compared with folate and pyridoxal and its subsequent urinary excretion. Journal of Nutritional Sci-ence and Vitaminology, 30, 475–82.
8. Bettendorff, L., Wins, P. & Schoffeniels, E. (1990) Regulation of ion uptake in membrane vesicles from rat brain by thiamine com-pounds. Biochemical and Biophysical Research Communications, 171, 1137–44.
9. Thornber, E. J., Dunlop, R. H. & Gawthorne, J. M. (1980) Thiamin deficiency in the lamb: changes in thiamin phosphate esters in the brain. Journal of Neurochemistry, 35, 713–17.
10. Matsuda, T. & Cooper, J. R. (1981) the separation and determi-nation of thiamin and its phosphate esters in brain. Analytical Biochemistry, 117, 203–7.
11. Tanaka, C. & Cooper, J. R. (1968) the fluorescent microscopic localization of thiamine in nervous tissue. Journal of Histochemistry and Cyto chemistry, 16, 362–5. 12. Fox, J. M. & Duppel,W.(1975) The action of thiamine and its di- and triphosphates on the slow exponential decline of the ionic currents in the node of Ranvier. Brain Research, 89, 287–302.
13. Nishino, K. & Itokawa, Y. (1977) Thiamin metabolism in vitamin B6 or vitamin B deficientrats. Journal of Nutrition, 107, 775–82.
14. Howard, L., Wagner, C. & Schenker, S. (1974) Malabsorption of thiamin in folatedeficient rats. Journal of Nutrition, 104, 1024–32.
15. Dreyfus, P. M. & Victor, M. (1961) Effects of thiamine deficiency on the central nervous system. American Journal of Clinical Nutrition, 9, 414–25.
16. Page, M. G., AnkomaSey, V., Coulson, W. F. & Bender, D. A. (1989) Brain glutamate and γ-aminobutyrate (GABA) metabolism in thiamin-deficient rats. British Journal of Nutrition, 62, 245–53.
17. White, H. L., Howard, J. L., Cooper, B. R., Soroko, F. E., Mc Dermed, J. D., Ingold, K. J. & Maxwell, R. A. (1982) A novel inhibitor of gamma aminobutyrate aminotransferase with anorectic activity. Journal of Neurochemistry, 39, 271–3.
18. Kimura, H. & Kuriyama, K. (1975) Distribution of gamma aminobutyric acid (GABA) in the rat hypothalamus: functional correlates of GABA with activities of appetite controlling mechanisms. Journal of Neurochemistry, 24, 903–7.
19. Blass, J. P. & Gibson, G. E. (1977) Abnormality of a thiamine-requiring enzyme in patients with Wernicke–Korsakoff syndrome.New England Journal of Medicine , 297, 1367–70.
20. Nixon, P. F., Kaczmarek, M. J., Tate, J., Kerr, R. A. & Price, J. (1984) An erythrocyte transketolase isoenzyme pattern associated with the Wernicke–Korsakoff syndrome. European Journal of Clinical Investigation, 14, 278–81.
21. Cumming, F., Briggs, M. & Briggs, M. (1981) Clinical toxicology of vitamin supplements. In Vitamins in Human Biology and Medicine. (Ed. M. H. Briggs), pp. 187–243. CRC Press, Inc., Boca Raton, Florida.
22. Food and Nutrition Board (1989). Recommended Dietary Allowances, 10th ed., National Research Council, National Academy of Sciences, Washington, DC
Noore, N. A., Sadiq, N. ., & Hakim, M. P. (2023). VITAMIN B1 (THIAMIN) AND ITS CHARACTERISTICS. Academic Research in Educational Sciences, 4(8), 61–71. https://doi.org/
Noore, Noor , et al. “VITAMIN B1 (THIAMIN) AND ITS CHARACTERISTICS.” Academic Research in Educational Sciences, vol. 8, no. 4, 2023, pp. 61–71, https://doi.org/.
Noore, A., Sadiq, ., and Hakim, P. 2023. VITAMIN B1 (THIAMIN) AND ITS CHARACTERISTICS. Academic Research in Educational Sciences. 8(4), pp.61–71.